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M94A2553.TXT
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1994-10-25
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Document 2553
DOCN M94A2553
TI HIV infection incidence based on seroprevalence data in Belo Horizonte,
Brazil.
DT 9412
AU Greco Dirceu B; Toledo Junior AC; Oliveira HC; Cordeiro P; Silva SR;
Antunes C; Federal University of Minas Gerais, Brazil.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):278 (abstract no. PC0032). Unique
Identifier : AIDSLINE ICA10/94370022
AB OBJECTIVE: Incidence data for HIV infection is lacking in most
countries. It is described the estimation of incidence based on
seroprevalence data. METHODS: From 1986 to 1992, 1,358
homosexual/bisexual male at risk for HIV were evaluated at the
Immunodeficiency Sector. Assuming that: 1) antibody to HIV is a
consistent and persistent marker of the infection, 2) in a fixed
population the rate of increase of seroprevalence reflects the rate at
which new infections occur among uninfected persons, 3) fixed subgroups
of general population can be defined by birth years, 4) since fixed
subgroups rates at which new infections occur determinate rates in
increase of seroprevalence, incidence rates can be estimated directly
from serial birth-cohort-specific seroprevalence data. Thus HIV
incidence was estimated based on data from 591 homosexual/bisexual HIV+
male diagnosed at this high risk clinic. RESULTS: The HIV infection
incidence rate had a mean of 8.0% per year (2.9-15.0%). The overall
incidence was 1.3% per year. CONCLUSION AND DISCUSSION: The HIV
infection incidence can be crudely estimated based on seroprevalence
data. It maybe an useful method to estimate incidence in most
institutions with seroprevalence data. The population here evaluated has
a high incidence of HIV infection and could be a good group for future
preventive vaccine trials.
DE Brazil/EPIDEMIOLOGY Human HIV Infections/*EPIDEMIOLOGY HIV
Seroprevalence Incidence Male Risk Factors Seroepidemiologic Methods
Sex Behavior MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).